Research databases

HDB-0011

ClinicalTrials.gov

US National Library of Medicine The world's largest registry of clinical studies, spanning interventional trials and observational studies in 200+ countries, with protocols, eligibility criteria and posted results. Fully open with a modern REST API. Research database Open access HDB-0012

PubMed / MEDLINE

US National Library of Medicine The primary index of biomedical literature: 37M+ citations with abstracts, MeSH indexing and links to full text. Free to search, with E-utilities APIs and annual baseline downloads for text mining. Research database Open access HDB-0032

Embase

Elsevier Biomedical abstract and indexing database containing 44+ million records from 8,100+ journals, conference abstracts, and clinical trials dating from 1947 to present. Designed for systematic reviews, drug safety monitoring, and evidence-based research; accessed through paid institutional subscriptions or individual access options. Research database Paid HDB-0033

Cochrane Library

Cochrane Curated collection of systematic reviews and meta-analyses synthesizing healthcare research, with all reviews available free after 12 months of publication. Supports evidence-based decision making through institutional subscriptions or free national provision access in 14+ countries. Research database Free registration HDB-0034

CINAHL

EBSCO Nursing and allied health literature index containing 1.25+ million records from 3,700+ journals, books, pamphlets, and dissertations. Provides CINAHL Subject Headings indexing with multiple product tiers offering varying levels of full-text access; accessed through institutional subscriptions or trials. Research database Paid HDB-0035

Scopus

Elsevier Multidisciplinary abstract and citation database indexing 100+ million records from journals, books, conference proceedings, and preprints across all research disciplines. Features AI-powered analytics and discovery tools; accessed through institutional subscriptions with free preview mode available to individuals. Research database Paid HDB-0036

Web of Science

Clarivate Citation-indexed research discovery platform covering 34,000+ journals with 278+ million records and 3.3+ billion citation links across 254 subject categories from 1864-present. Includes specialty databases for patents, dissertations, and preprints; accessed through institutional subscriptions only. Research database Paid HDB-0037

APA PsycInfo

American Psychological Association Behavioral and social sciences database indexing 6+ million peer-reviewed records from 2,400+ journals, books, and dissertations in 30 languages from 50 countries. Updated twice weekly with coverage spanning 600 years; accessed through institutional licenses or individual subscriptions with free 30-day trials available. Research database Paid HDB-0039

Trip Database

Trip (independent organization) Evidence-filtered medical search engine providing rapid access to clinical guidelines, systematic reviews, and primary research organized by research quality level. Offers free basic search and paid Trip Pro tier ($55/year individual or institutional licensing) with enhanced filtering and features. Research database Free registration HDB-0082

Kenya Medical Research Institute (KEMRI)

Kenya Medical Research Institute KEMRI is Kenya's leading health research institute established in 1979, conducting research on infectious diseases, parasitic diseases, epidemiology, and non-communicable diseases with state-of-the-art laboratories and extensive surveillance networks. The institute operates the Kilifi Health and Demographic Surveillance System (KHDSS), a Clinical Information Network spanning 25 hospitals, and maintains a biobank of over one million samples. Research database Credentialed HDB-0086

Pan African Clinical Trials Registry (PACTR)

South African Medical Research Council (SAMRC) PACTR is the first WHO-recognized primary clinical trials registry in Africa, providing a free, open-access platform for registration of planned, ongoing, and completed clinical trials conducted across the continent. Established in 2007 and expanded to all disease conditions in 2009, the registry documents research patterns, funding, ethics, and locations of African-based trials. Research database Open access HDB-0090

Japan MID-NET (Medical Information Database Network)

Pharmaceuticals and Medical Devices Agency (PMDA) A distributed medical information database established in 2018 aggregating electronic health records, insurance claims data, and diagnosis procedure combination information from healthcare institutions. The database supports real-world drug safety assessments and pharmacoepidemiological research with rigorous quality management standards. Research database Credentialed HDB-0092

National Health Information Database / National Health Insurance Service Data

National Health Insurance Service (NHIS) A research data platform providing access to universal health insurance and health screening data covering over 50 million members of South Korea's national insurance system. The database includes eligibility data, health screening results, healthcare utilization records, prescriptions, and mortality information for the entire insured population. Research database Credentialed HDB-0093

Health Insurance Review and Assessment Service Data (HIRA)

Health Insurance Review and Assessment Service A comprehensive claims repository containing healthcare reimbursement data from 98% of South Korea's population covering 56+ million patients (2015-2024 in standardized OMOP-CDM format). The database includes patient demographics, diagnoses, prescriptions, procedures, and surgical information supporting health services research. Research database Open access HDB-0095

Clinical Data Analysis and Reporting System (CDARS)

Hospital Authority A comprehensive clinical data repository managed by Hong Kong's Hospital Authority covering over 11 million individuals (90%+ of population) with electronic health records from 43 hospitals and 122 outpatient clinics. The database contains diagnosis codes, medication records, procedures, laboratory results, and admission/discharge details supporting territory-wide epidemiological research. Research database Credentialed HDB-0097

ICMR National Health Research Data Repository

Indian Council of Medical Research (ICMR) Centralized repository of anonymized high-quality health research datasets maintained by ICMR to support health research and innovation in India. Researchers must register and gain credentialed access to query datasets covering areas including gastrointestinal disorders, cerebral thrombosis, pesticide exposure, and infectious diseases. Research database Credentialed HDB-0098

ICMR-NINE National Cancer Registry Programme

ICMR - National Institute of NCD Epidemiology (formerly NCDIR) National cancer registry program established in 1982, operating through 38 population-based cancer registries (PBCRs) and 269 hospital-based registries (HBCRs) covering approximately 11 percent of India's population. Registry data supports understanding cancer epidemiology, trends, and patterns across India; registries operate as part of broader NCD surveillance including diabetes, cardiovascular disease, and stroke. Research database By application HDB-0102

Singapore National Registry of Diseases Office (NRDO)

National Registry of Diseases Office (NRDO), Ministry of Health Singapore Government registry established under the National Registry of Diseases Act (2007) that maintains disease registries for major conditions including cancer (established 1968), myocardial infarction, renal failure, and stroke. Registries collect clinical and epidemiological data from healthcare institutions to track disease burden, trends, and outcomes. Research database Credentialed HDB-0105

Bangladesh icddr,b Matlab Health and Demographic Surveillance System

icddr,b (International Centre for Diarrhoeal Disease Research, Bangladesh) The longest-running health and demographic surveillance system in the global South, operating since 1966 in Matlab, Bangladesh, tracking births, deaths, migrations, marriages, and divorces across a rural population of approximately 220,000. Matlab HDSS is a member of the INDEPTH network and serves as a research platform for health and demographic studies in developing country contexts. Research database By application HDB-0107

Clalit Research Institute

Clalit Health Services Clalit Research Institute maintains one of the world's richest integrated healthcare data repositories spanning over 30 years of fully digitized medical records from over 5.5 million members of Clalit Health Services. The institute provides access to longitudinal clinical data including diagnoses, hospitalizations, medications, laboratory results, and medical procedures for research applications. Research database Credentialed HDB-0108

KSM Research and Innovation Center

Maccabi Healthcare Services KSM Research and Innovation Center maintains research access to Maccabi Healthcare Services' digital medical records covering 2.6 million members with 30 years of longitudinal data, plus Israel's largest biobank containing over 1 million samples. The center supports research through multiple divisions including innovation and big data analytics, epidemiology, and clinical research infrastructure. Research database Credentialed HDB-0109

Golestan Cohort Study

Digestive Diseases Research Institute, Tehran University of Medical Sciences; National Cancer Institute (NCI) The Golestan Cohort Study is a population-based prospective cohort of approximately 50,000 adults aged 40-75 years in Golestan Province, Iran, established to investigate environmental and genetic risk factors for esophageal squamous cell carcinoma. Participants provided biological specimens (blood, hair, nails, urine) and detailed lifestyle and dietary questionnaire data, with ongoing annual follow-up monitoring. Research database By application HDB-0112

Danish National Patient Registry (Landspatientregisteret)

Danish Health Data Authority (Sundhedsdatastyrelsen) The Danish National Patient Registry contains comprehensive data on all hospital admissions, diagnoses coded in ICD-10, procedures coded in NOMESCO, and treatments in Denmark since 1977, covering both psychiatric and non-psychiatric inpatient care as well as emergency and outpatient specialty visits since 1995. Access for research is granted through application to the Danish Health Data Authority, which manages the registry as part of a broader health data system covering operations, diagnoses, births, causes of death, and medicines. Research database By application HDB-0113

Danish Civil Registration System (Det Centrale Personregister)

Ministry for Economic Affairs and the Interior (Denmark) The Danish CPR is a national register established in 1968 that maintains civil registration numbers, names, addresses, birth records, citizenship, church affiliation, parentage, and marital status for all Danish residents and Greenlandic citizens. Data is accessible to government agencies, businesses, organizations, and research institutions through data purchase arrangements, and individuals can request access to their own records. Research database Credentialed HDB-0114

Statistics Denmark

Statistics Denmark (Danmarks Statistik) Statistics Denmark is the central authority on Danish statistics that provides researchers and analysts access to a wide range of pseudonymised microdata about Danish society through its digital platform (DDP App). Authorised institutions can submit project proposals for approval to access microdata for research and analysis purposes. Research database Credentialed HDB-0115

Swedish National Patient Register (Nationella Patientregistret)

Socialstyrelsen (National Board of Health and Welfare, Sweden) The Swedish National Patient Register contains data on all inpatient hospital episodes since 1964 and outpatient specialist care visits, day surgery, and psychiatric care since 2001, including diagnoses, procedures, and administrative information. Access for research requires approval from the Swedish Ethical Review Authority following a formal application process. Research database By application HDB-0116

Swedish Prescribed Drug Register (Läkemedelsregistret)

Socialstyrelsen (National Board of Health and Welfare, Sweden) The Swedish Prescribed Drug Register contains records of all prescribed drugs dispensed in Swedish pharmacies since July 2005, with over 100 million entries annually, including patient age, sex, unique identifier, prescriber information, and dispensation details. The register is updated monthly and used by researchers, public agencies, journalists, and pharmaceutical industry representatives to study prescription patterns and drug safety. Research database By application HDB-0117

Norwegian Patient Registry (Norsk Pasientregister)

Norwegian Institute of Public Health (NIPH) The Norwegian Patient Registry contains information on all individuals who have received or are waiting to receive treatment in the specialist health service since 2008, including administrative, medical, and social information about healthcare episodes. Data access for research and other purposes requires submission of an application form to the Norwegian Institute of Public Health. Research database By application HDB-0118

Norwegian Prescribed Drug Registry (Legemiddelregisteret)

Norwegian Institute of Public Health (FHI) The Norwegian Prescribed Drug Registry is the successor to the Norwegian Prescription Database (NorPD) and contains records of all prescription drugs dispensed in Norwegian pharmacies since 2004, anonymised and pseudonymised for research use. Applications for research data access must be submitted to the Norwegian Institute of Public Health. Research database By application HDB-0119

FinnGen

FinnGen (public-private partnership) FinnGen is a large research project that has collected genome and longitudinal health data from over 500,000 Finnish biobank participants (approximately 10% of Finland's population), comprising more than 21.3 million genetic variants and over 2,750 health endpoints. Genome-wide association study (GWAS) results are publicly available for browsing and download, while complete dataset access is available to researchers at Finnish universities and university hospitals. Research database Free registration HDB-0120

Findata (Finnish Social and Health Data Permit Authority)

Findata (Finland) Findata is the Finnish authority that grants permits for the secondary use of health and social care data from multiple public and private data controllers, providing researchers access to pseudonymised registry data through a formal permit application process that typically requires 2-4 months for decision. The authority also pre-processes approved datasets and offers analytical tools for approved research uses. Research database By application HDB-0121

NORDCAN (Nordic Cancer Statistics Database)

Association of Nordic Cancer Registries (ANCR) and International Agency for Research on Cancer (IARC) NORDCAN is a web-based tool providing cancer statistics from Nordic countries (Denmark, Finland, Iceland, Norway, Sweden, Faroe Islands, and Greenland) including incidence, mortality, survival, and prevalence data spanning up to 70 years, with the earliest records from Denmark's National Cancer Registry established in 1943. Data is updated annually and presented as anonymous, privacy-protected statistics that can be compared across countries, regions, cancer types, and demographic groups. Research database Open access HDB-0122

SNDS (Système National des Données de Santé)

Cnam (National Health Insurance Fund) The SNDS integrates health insurance reimbursement data (Sniiram), hospital activity records (PMSI), mortality data from Inserm, and disability support data, covering over 65 million individuals. Access is provided through the Health Data Hub to public organizations with permanent public service missions and to entities authorized by CNIL (France's data protection authority) for public interest research. Research database Credentialed HDB-0123

Health Data Hub (Plateforme des données de santé)

GIP Santé (Public Interest Grouping), joint supervision of Ministry of Health, INRIA, INSERM, CNAM The Health Data Hub is France's national platform providing secure, unified access to pseudonymized health data from SNDS and other national health registries, serving researchers, innovators, and public health authorities. Data access requires project submission, CNIL authorization, and demonstration of public interest; over 230 projects have been approved through the platform. Research database By application HDB-0124

Forschungsdatenzentrum Gesundheit (FDZ Gesundheit)

BfArM (Federal Institute for Drugs and Medical Devices) The FDZ Gesundheit provides pseudonymized billing data from all legally insured Germans through virtual analysis workspaces, with plans to add electronic patient record (ePA) data as of late 2026. Researchers submit applications detailing their research purpose, and approved researchers access customized datasets within secure analysis environments without direct data transfer. Research database By application HDB-0125

German Centre for Cancer Registry Data (Zentrum für Krebsregisterdaten, ZfKD)

Robert Koch Institute (RKI) The ZfKD consolidates clinical and epidemiological cancer registry data from all 16 German federal states, providing incidence, prevalence, and survival statistics across 30+ cancer types with 25 years of historical data. Access is provided through an interactive database query interface and regular epidemiological publications; data through 2023 is available. Research database Open access HDB-0126

PHARMO Database Network

PHARMO Institute (now part of Lumanity) The PHARMO Database Network comprises anonymized linked healthcare records from 14 million patients across 1,400 primary and secondary care providers in the Netherlands, representing 250 million person-years of data including GP records, hospital admissions, pharmacy records, and specialized registries. Researchers access PHARMO through coordinated studies via institutional partnerships; the database has contributed to over 1,000 published studies covering drug safety, effectiveness, and utilization. Research database Credentialed HDB-0127

Nivel Primary Care Database (Nivel-PCD)

Nivel (Netherlands Institute for Health Services Research) The Nivel Primary Care Database combines routine electronic health record data from representative samples of Dutch primary care providers (GPs, physiotherapists, mental health professionals, dietitians) linked with pharmacy and secondary care data. Researchers access de-identified data through a formal application and approval process governed by steering committees with healthcare provider representatives. Research database Credentialed HDB-0128

Healthdata.be / Health Data Agency (HDA)

Health Data Agency (formerly Sciensano) Healthdata.be is a Belgian platform that facilitates data exchange between healthcare professionals and researchers while protecting privacy and medical confidentiality, providing inventory of national health registries and secure data collection infrastructure. As of April 1, 2026, the platform is managed by the Health Data Agency; access procedures and registry management are coordinated through the updated platform at hda.belgium.be. Research database By application HDB-0129

Clinical Practice Research Datalink (CPRD)

Medicines and Healthcare products Regulatory Agency (MHRA) CPRD is a database of de-identified patient records from a network of UK general practices, covering approximately 60 million historical patients with 18 million currently registered, operated by the MHRA with support from the National Institute for Health and Care Research. Researchers access CPRD data for observational studies, clinical research, and surveillance through an application and review process conducted by the CPRD team. Research database By application HDB-0130

Hospital Episode Statistics (HES)

NHS England Digital HES is a national administrative database containing over 1 billion records of all NHS hospital admissions, outpatient appointments, and emergency department attendances in England, maintained by NHS England Digital. Researchers and organizations access HES data through data access request services for health services research, epidemiology, and policy evaluation. Research database By application HDB-0131

OpenSAFELY

Bennett Institute for Applied Data Science, University of Oxford, in partnership with NHS England, TPP, and Optum OpenSAFELY is a trusted research environment and open-source analytics platform that enables researchers to conduct statistical analyses on pseudonymized primary care records from across the UK without direct access to individual patient data. Approved researchers submit analysis code that executes on the platform, with only aggregated results returned to researchers, ensuring privacy protection while supporting 200+ active projects. Research database Credentialed HDB-0132

SAIL Databank (Secure Anonymised Information Linkage)

Swansea University Medical School, funded by Health and Care Research Wales SAIL Databank is a trusted research environment containing anonymised health and social care records for approximately 5.5 million people in Wales, integrating data from NHS services, social care, educational records, and other administrative sources, with 25+ years of historical coverage and ISO 27001 certification. Researchers apply through a governance review process to access linked datasets for epidemiological, health services, and policy research. Research database Credentialed HDB-0133

Scotland National Safe Haven (eDRIS)

Public Health Scotland, Electronic Data Research and Innovation Service (eDRIS), hosted by EPCC and University of Edinburgh The Scotland National Safe Haven is a trusted research environment providing secure access to sensitive NHS patient records for approved research projects, governed by Scotland's Public Benefit and Privacy Panel. Accredited researchers submit applications for access to linked NHS data for epidemiology, health services research, and public health surveillance. Research database Credentialed HDB-0134

IQVIA Medical Research Data (IMRD)

IQVIA (previously known as The Health Improvement Network - THIN) IQVIA Medical Research Data is a longitudinal database of de-identified electronic health records from more than 6 million patients in England, derived from participating general practices using EMIS Health, Cegedim, and other clinical systems, and approved by the NHS Health Research Authority for medical research. Researchers access IMRD through application and data-sharing agreements for observational studies, pharmacovigilance, and comparative effectiveness research. Research database By application HDB-0135

Genomics England: 100,000 Genomes Project

Genomics England, funded by the UK Department of Health and Social Care The 100,000 Genomes Project is a genomic database containing whole genome sequences from approximately 85,000 NHS patients affected by rare diseases or cancer, established between 2013 and 2018, with data linked to NHS clinical records and participant consent status. Qualified researchers can access the project's genomic and phenotypic data through application for research on disease genetics, therapeutic development, and diagnostics. Research database By application HDB-0136

Our Future Health

Our Future Health, a public-private partnership involving NHS England, UK Research and Innovation, Wellcome Trust, and industry partners Our Future Health is a health cohort and biobank recruiting up to 5 million UK participants with linked health records, physical measurements, biosamples, and genetic data, designed to enable large-scale research on disease prevention and treatment. Qualified researchers access de-identified participant data through a secure trusted research environment for studies on disease patterns, risk factors, and health outcomes across diverse populations. Research database By application HDB-0137

UK Data Service

UK Data Service (part of Jisc), funded by the Economic and Social Research Council and supported by partner institutions The UK Data Service maintains the UK's largest collection of research data, including health surveys (Health Survey for England, Adult Psychiatric Morbidity Survey, National Child Measurement Programme) and social research datasets covering health outcomes, healthcare access, and population health. Researchers access health datasets for secondary analysis and educational purposes through online discovery tools with free or subscription-based registration. Research database Free registration HDB-0138

Hospital In-Patient Enquiry (HIPE)

Healthcare Pricing Office (HPO), Irish Department of Health HIPE is a national computerised health information system recording demographic, administrative, and clinical data on all inpatient and daycase discharges from publicly funded acute hospitals in Ireland, covering approximately 1.7 million discharges annually from 58 public acute hospitals. Researchers access HIPE data through the HPO for health services research, epidemiology, clinical audit, and policy planning using the HIPE Statistics Reporter or data requests. Research database By application HDB-0143

45 and Up Study (The Sax Institute)

Sax Institute, in collaboration with Cancer Council NSW and NSW Ministry of Health Australia's largest ongoing longitudinal study of health and ageing enrolls over 250,000 participants aged 45+ and tracks them across 15+ years of follow-up data. The study provides access to survey questionnaires, physical assessments, biospecimens (blood, genetic data), and linked data from Medicare, pharmaceutical records, hospital episodes, and cancer registries. Research database By application HDB-0144

ICES (formerly Institute for Clinical Evaluative Sciences) - Ontario

ICES ICES is an independent health data analytics institute housing comprehensive Ontario health system data collected since 1992 from healthcare interactions including hospital, primary care, and social service records. Researchers access linked administrative health data for studies in cancer, cardiovascular disease, mental health, and health equity through formal research agreements. Research database By application HDB-0145

Canadian Institute for Health Information (CIHI)

Canadian Institute for Health Information CIHI is an independent, not-for-profit organization providing standardized health system data and indicators for Canadian provinces and territories, including hospital, pharmaceutical, and health services data. The institute publishes reports, dashboards, and data tables through its indicator library and provides secure analytical tools (Insight+) for deeper analysis of health system performance. Research database Free registration HDB-0146

Canadian Longitudinal Study on Aging (CLSA)

Canadian Longitudinal Study on Aging CLSA is a national longitudinal research platform following 51,000+ participants aged 45-85 across 20 years to examine biological, medical, psychological, social, and economic aspects of aging, disability, and disease. The study provides researchers and international collaborators access to questionnaire data, physical assessments, biomarkers, genomics, metabolomics, imaging, and linked health outcome data including COVID-19 serology. Research database By application HDB-0147

WHO ICTRP (International Clinical Trials Registry Platform)

World Health Organization ICTRP is a WHO-operated search portal that aggregates clinical trial registration data from 21 primary registries across multiple countries and regions, including trials in all phases and across all therapeutic areas. The platform provides a unified search interface for finding trial information while linking to the original records maintained by contributing registries. Research database Open access HDB-0148

EudraCT

European Medicines Agency (EMA) EudraCT is the European Union's database for interventional clinical trials on medicinal products conducted in the EU/EEA from May 2004 through January 2025 under Directive 2001/20/EC. As of January 31, 2025, new EU/EEA trials must transition to the newer Clinical Trials Information System (CTIS), though EudraCT continues to accept results submissions and third-country trial files. Research database Open access HDB-0149

EU Clinical Trials Register

European Medicines Agency (EMA) The EU Clinical Trials Register provides public access to information on trials previously registered in EudraCT, including trial protocols and results data. It serves as the historical and transitional repository for EU/EEA trial information while ongoing trials are registered through the newer Clinical Trials Information System. Research database Open access HDB-0150

ISRCTN Registry

BioMed Central / Springer Nature ISRCTN is the UK's only WHO-recognised primary clinical study registry, accepting registration of interventional and non-interventional studies at any stage (proposed, ongoing, or completed). All records are freely searchable and openly accessible, supporting UK transparency requirements effective April 2026 that mandate prospective registration and results publication within 12 months. Research database Open access HDB-0151

CTRI (Clinical Trials Registry - India)

Indian Council of Medical Research, National Institute for Research in Digital Health CTRI is a free public registry for registration of all clinical trials conducted in India, mandatory since 2009 and accessible through both the CTRI website and WHO's ICTRP. The registry contains over 115,000 trials including drug trials, surgical procedures, device studies, behavioral interventions, and AYUSH research, all prospectively registered before participant enrollment. Research database Open access HDB-0152

ChiCTR (Chinese Clinical Trial Registry)

Chinese Clinical Trial Registry Center ChiCTR is a WHO-recognised primary registry for clinical trials conducted in China, offering searchable access organized by geographic location, disease codes, funding source, recruitment status, and ethical committee approval. The platform includes a user account system for researchers to register and manage trials, with free registration and comprehensive methodology resources available. Research database Free registration HDB-0153

ReBEC (Brazilian Clinical Trials Registry)

Ministry of Health / Pan American Health Organization / Oswaldo Cruz Foundation ReBEC is a free-access virtual platform for registration of experimental and non-experimental studies conducted in Brazil, hosted by a collaborative effort of government and international health organizations. The registry contains over 18,700 trials including 5,162 actively recruiting studies, with multilingual support (Portuguese and English) and dedicated user assistance available 24/7. Research database Free registration HDB-0154

OHDSI

OHDSI Collaborative OHDSI is an international open-science collaborative that standardizes and coordinates observational health databases through the OMOP Common Data Model for large-scale analytics and real-world evidence generation. The network operates through a decentralized community of researchers and data partners who can conduct collaborative studies using harmonized health data while maintaining local data governance. Research database Free registration HDB-0155

EHDEN

EHDEN Foundation EHDEN operates a federated network of over 100 healthcare data sources across Europe standardized to the OMOP Common Data Model to generate reliable real-world evidence for medicines and health research. The foundation provides infrastructure, training, and research coordination services to enable collaborative studies while maintaining data governance and institutional autonomy. Research database By application HDB-0156

DARWIN EU

European Medicines Agency (EMA) DARWIN EU is the EMA's Data Analysis and Real World Interrogation Network, established to provide timely evidence on the safety and effectiveness of medicines using real-world healthcare data from approximately 40 data partners across the EU. The network conducts regulatory studies to support medicines oversight and authorization decisions throughout a medicine's lifecycle. Research database By application HDB-0157

FDA Sentinel Initiative

FDA (US Food and Drug Administration) The FDA Sentinel Initiative is a distributed system for evaluating the safety and performance of medical products using real-world data from insurance claims, electronic health records, and patient reports covering approximately 138.7 million members. Data remain with their sources (insurance companies, EHR systems, etc.) and are analyzed through a decentralized model that preserves privacy and data security. Research database By application HDB-0158

PCORnet

PCORI (Patient-Centered Outcomes Research Institute) PCORnet is a national research network funded by PCORI that aggregates health data from diverse clinical settings to enable patient-centered comparative effectiveness research and fast, trustworthy evidence generation. The network provides researchers and healthcare organizations with access to comprehensive clinical data and research infrastructure while incorporating patient perspectives in research design. Research database By application HDB-0161

HDR UK Innovation Gateway

HDR UK (Health Data Research UK) HDR UK Gateway is a centralized platform that enables researchers to discover, access, and link UK health datasets for research, including integration with the Cohort Discovery Service for secure exploration of patient cohorts across multiple datasets. The platform streamlines the researcher journey from feasibility assessment through data access agreements with NHS trusts, academic institutions, and other data holders. Research database Free registration HDB-0175

Grand Challenge

Diagnostic Image Analysis Group (DIAG), Radboud University Medical Center A platform hosting 419+ open medical imaging challenges and datasets across diverse imaging modalities and anatomical sites. Participants can submit algorithms, access benchmark datasets, and benchmark their models against peer submissions in real time. Research database Free registration HDB-0178

National Health Insurance Research Database (NHIRD, Taiwan)

Health and Welfare Data Science Center, Ministry of Health and Welfare (Taiwan) De-identified claims data from Taiwan's single-payer National Health Insurance scheme, which covers essentially the whole population, including diagnoses, prescriptions, procedures and examinations. Access is granted through the Ministry of Health and Welfare's Health and Welfare Data Science Center, where approved researchers analyse the data on-site or in a controlled environment rather than downloading it. Research database By application HDB-0179

NDB — National Database of Health Insurance Claims (Japan)

Ministry of Health, Labour and Welfare (Japan) Japan's national repository of anonymized health insurance claims and Specific Health Checkup records, collected under the Ministry of Health, Labour and Welfare with data from April 2009 onward. Researchers apply to MHLW for provision of the anonymized data, which is used for health policy analysis and pharmacoepidemiology; MHLW also publishes aggregated NDB open data tables. Research database By application